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September 11, 2025

Corneal Cross-linking in Pediatric Populations: Systematic Review and Future Perspectives.

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Authors

CMCláudia do Rosário Vaz MorgadoNLNicole B. LarivoirJSJennifer F. De Los Santos

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Overview

Systematic review analyzes corneal cross-linking techniques in pediatric patients, suggesting effective stabilization rates.

Key Points

  • Standard and accelerated corneal cross-linking effectively stabilize keratoconus in pediatric populations, achieving rates higher than 80%.
  • Analysis involved 2,186 eyes across 35 studies, exploring maximum keratometry before and after procedures.
  • The systematic review adheres to PRISMA guidelines, ensuring comprehensive evaluation of standard and accelerated CXL protocols.
  • Younger age and severity of keratoconus impact stabilization results, highlighting the need for tailored therapeutic approaches.

Cite This Study

Morgado et al. (2025) studied this question.

synapsesocial.com/papers/68c2a9c304ab598fffb89ccfhttps://doi.org/10.3928/1081597x-20250624-03
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Corneal Cross-Linking for Pediatric Keratoconus2024 · 2 citations
  2. 2Corneal Cross-Linking in Keratoconus: A Scoping Review of Clinical Evidence and Public Health Implications2025
  3. 3Efficacy and Safety of 7.2 J/cm² Accelerated Corneal Cross-Linking in Pediatric and Adult Keratoconus: A Comparative Study.2025
  4. 4Corneal Crosslinking in Keratoconus in Children, Evaluation of Efficiency in the Remote Period. Clinical Case with 5-year Follow-up2025 · 2 citations
  5. 5Long-Term Outcomes of Corneal Crosslinking for Keratoconus Across Pediatric, Adolescent, and Adult Populations in a Diverse U.S. Population2026