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September 16, 2025

The Role of Galectin-3 as a Biomarker in the Cardio-Renal-Metabolic Pathology Axis.

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Authors

OBOana Nicoleta Buliga-FinișAOAnca OuatuDTDaniela Maria Tănase

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Overview

This review highlights galectin-3's role as a biomarker for cardiovascular and renal dysfunction in diabetes, suggesting improved patient management.

Key Points

  • Elevated galectin-3 levels are linked to an increased risk of mortality and renal failure in patients with diabetes, indicating its significant role in cardiac and renal health.
  • An early decline in glomerular filtration rate in diabetic patients can occur without albumin excretion, emphasizing the need for reliable biomarkers like galectin-3.
  • Research indicates that including galectin-3 assessments in clinical practice can enhance diagnostic precision for cardio-renal disorders.
  • Galectin-3 may serve as an important indicator for both diagnostic and therapeutic strategies in cardiovascular and renal diseases.

Cite This Study

Buliga-Finiș et al. (2025) studied this question.

synapsesocial.com/papers/68c93fe601120bef803baddbhttps://doi.org/10.3390/jcm14176071
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Also Consider

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  3. 3Galectin-3, Renal Function, and Clinical Outcomes2015 · 128 citations
  4. 4Renal Handling of Galectin‐3 in the General Population, Chronic Heart Failure, and Hemodialysis2014 · 66 citations
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