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October 1, 2025Medical Journal of BabylonOpen Access

Assessment of Galectin-3 with Biochemical Changes in Patients with Chronic Kidney Disease

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Authors

DKDunia Abbas KhudhairSKS. KadhimUniversity of TabrizHKHadeel Luay KareemUniversity of Babylon

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Overview

This case-control study shows significant links between galectin-3 levels and kidney function in CKD patients, suggesting potential diagnostic value.

Key Points

  • Galectin-3 concentration significantly increased in patients with chronic kidney disease compared to controls.
  • The area under the curve for galectin-3 in assessing kidney disease was found to be 77%, indicating substantial diagnostic potential.
  • Statistical methods confirmed a significant association between glomerular filtration rate and plasma Gal-3 levels in CKD patients.
  • This analysis involved 90 patients, providing a robust framework for understanding biochemical changes related to chronic kidney disease.

Cite This Study

Khudhair et al. (2025) studied this question.

synapsesocial.com/papers/68dd9537fe798ba2fc49960ahttps://doi.org/10.4103/mjbl.mjbl_763_24
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Galectin-3 in recipients with kidney graft dysfunction: analysis of predictive significance2024
  2. 2Evaluation of Serum Galectin-3 Levels Across Chronic Kidney Disease Stages and Its Association with Cardiovascular Complications in Maintenance Hemodialysis Patients2026
  3. 3The Role of Galectin-3 as a Biomarker in the Cardio-Renal-Metabolic Pathology Axis.2025 · 10 citations
  4. 4Circulating galectin-3 level association with cardiovascular risk factors during peritoneal dialysis2024 · 3 citations
  5. 5A pilot study of Galectin-3 targeting in chronic kidney fibrosis and kidney function decline2026