Novel method synthesizes high-yield symmetric biaryls using nickel and photo-redox catalysis, indicating efficiency.
A novel reductive approach towards symmetric biaryls has been developed based on Ni/photo-redox catalysis. Employing NEt3 as a cheap and energetically favorable, weak reducing agent in the homo-coupling of conveniently accessible (pseu-do)halides, highly functionalized biaryls were obtained in general high yields. Highlighting the synthetic value of our herein reported method, different potentially interesting compounds and the hepatitis C drug daclatasvir were synthesized.
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Strey et al. (2025) studied this question.
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