Reductive coupling of aryl (pseudo)halides towards symmetrical biaryls via a dual Ni/photoredox catalysis

Sadiq Strey; Kristin Olbricht; D. Sommer; Dino Berthold

doi:10.1039/d6qo00661b

January 1, 2026Organic Chemistry FrontiersOpen Access

Reductive coupling of aryl (pseudo)halides towards symmetrical biaryls via a dual Ni/photoredox catalysis

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Key Points

The research aims to explore a dual catalysis approach for synthesizing symmetrical biaryls using mild reducing agents.
Utilized dual Ni/photoredox catalysis for the reductive coupling process.
Employed simple amines such as NEt₃ as reducing agents.
Supported by mechanistic insights and DFT studies.
Successfully synthesized various symmetrical biaryls under mild conditions.
Demonstrated the effectiveness of simple amines as reducing agents in the catalytic process.

Implication

Demonstrates reductive coupling of aryl halides to produce symmetrical biaryls, indicating a new method for synthesis.

Abstract

We demonstrate that dual Ni/photoredox catalysis enables a general reductive approach to symmetrical biaryls using simple amines as mild reducing agents. Guided by mechanistic considerations and DFT studies, NEt₃ was...

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Cite This Study

Strey et al. (2026) studied this question.

synapsesocial.com/papers/6a338b4c630953a74978cfe2 https://doi.org/10.1039/d6qo00661b

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Reductive coupling of aryl (pseudo)halides towards symmetrical biaryls via a dual Ni/photoredox catalysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Reductive coupling of aryl (pseudo)halides towards symmetrical biaryls via a dual Ni/photoredox catalysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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