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September 12, 2025VirusesOpen Access

Viral Burden of Respiratory Syncytial Virus and Viral Coinfections as Factors Regulating Paediatric Disease Severity

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Authors

VMVelia Chiara Di MaioBambino Gesù Children's HospitalRSRossana ScutariBambino Gesù Children's HospitalMMMatthew D. MastropaoloNeumann University

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Overview

This study reveals RSV infection severity in children, associating viral co-infections and clinical outcomes.

Key Points

  • In a cohort of 9877 children, 9.6% tested positive for RSV, revealing critical insights on the disease's burden.
  • Mono-infection with RSV was identified in 286 patients, while 351 had viral co-infections, indicating their prevalence.
  • Pneumonia was significantly linked to co-infection, while bronchiolitis was more common among mono-infected individuals.
  • Regression analysis showed age and cycle-threshold significantly influenced disease severity in RSV-infected children.

Cite This Study

Maio et al. (2025) studied this question.

synapsesocial.com/papers/68d44a3731b076d99fa53700https://doi.org/10.3390/v17091236
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