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September 12, 2025Annals of MedicineOpen Access

A review of neuroprotective properties of Centella asiatica (L.) Urb. and its therapeutic effects

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Authors

JJJiamei JiangRHRanran HanHRHonglei Ren

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Overview

Review reveals centella asiatica's neuroprotective properties and its implications for neurological disorders.

Key Points

  • Centella asiatica shows significant neuroprotective effects, reducing oxidative stress and inflammation.
  • In epilepsy models, asiatic acid improves synaptic function and decreases neuronal damage.
  • CA extracts enhance memory and cognitive functions by activating antioxidant pathways.
  • Centella asiatica exhibits broad neuroprotective potential with low toxicity, supporting its therapeutic use.

Cite This Study

Jiang et al. (2025) studied this question.

synapsesocial.com/papers/68d44a4731b076d99fa53e88https://doi.org/10.1080/07853890.2025.2559122
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Centella asiatica extract attenuates on glutamate-induced neurotoxicity in HT22 cells and scopolamine-induced animal model of cognitive impairment 91252025
  2. 2Centella asiatica ameliorates scopolamine-induced cognitive impairment via acetylcholinesterase modulation and oxidative stress reduction2026
  3. 3Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review2024 · 15 citations
  4. 4Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging2026 · 1 citations
  5. 5Centella asiatica suppresses inflammation and apoptosis and regulates the Gsk-3β signaling pathway in aluminum chloride-induced neurodegeneration in rats2026