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September 12, 2025Child s Nervous SystemOpen Access

Intraoperative magnetic resonance imaging during surgical resection for drug resistant epilepsy eliminates the incidence of inadvertent incomplete resection of the epileptogenic zone and early surgical failure

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Authors

JKJoyce KoueikYYYoungwon YounSRSusan Rebsamen

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Overview

Case series shows intraoperative MRI eliminates incomplete resection of the epileptogenic zone, supporting seizure control.

Key Points

  • Intraoperative MRI significantly reduces the rate of inadvertent incomplete resections during epilepsy surgery.
  • Seizure improvement was observed in 90% of pediatric subjects post-surgery, indicating enhanced outcomes from MRI guidance.
  • Thirty pediatric patients with drug resistant epilepsy were evaluated over an average follow-up of 4.2 years.
  • The presence of incomplete resections related to functional constraints was linked to poorer seizure control outcomes.

Cite This Study

Koueik et al. (2025) studied this question.

synapsesocial.com/papers/68d44b3031b076d99fa548achttps://doi.org/10.1007/s00381-025-06925-y
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integration of intraoperative ultrasound and depth-electrode electrocorticography for resection guidance in epilepsy surgery: technical workflow and feasibility2026
  2. 2Intraoperative MRI in pediatric brain tumor surgery: Optimizing surgical decision-making and extent of resection2026
  3. 3Role of Intraoperative Ultrasonography in Comparison with Early Postoperative MRI in Drug-Resistant Epilepsy Associated with Focal Cortical Dysplasia2026
  4. 4Combined Surgical Resection and Responsive Neurostimulation for Drug-Resistant Epilepsy: A Case Series2026
  5. 5Robot-assisted insular stereoelectroencephalography in pediatric drug- resistant epilepsy: accuracy and diagnostic value2024