September 16, 2025European PsychiatryOpen Access

The burden of birth control: a narrative review on the mood-related side effects of hormonal contraception

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Hormonal contraception use is associated with mood changes and depressive symptoms among females.
Factors influencing mood effects include type of hormonal contraception, dosage, and psychiatric history.
Adolescent females and those with a history of mood disorders are at higher risk for adverse effects.
Most females report no mood changes or even benefits from hormonal contraception usage.

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Narrative review reveals links between hormonal contraception, mood changes, and depressive symptoms.

Brás et al. (2025) studied this question.

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