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This is a Cross-Sectional Study study.

September 16, 2025European PsychiatryOpen Access

High-sensitivity C-reactive protein and cyclothymic temperament as predictors of suicidal risk

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Observational study evaluates hsCRP and cyclothymic temperament impacting suicidal risk in mood disorders, indicating potential biomarkers.

HsCRP levels significantly predict suicidal risk in patients with mood disorders, highlighting its potential as a biomarker.
Logistic regression showed that cyclothymic temperament positively correlates with suicidal risk, emphasizing personality traits' role.
Patients' mental health status and hsCRP levels correlated with a 76.8% classification accuracy in predicting suicidality risk.
The findings suggest integrating hsCRP testing in clinical practice, which may enhance early identification of suicidal risk.

Cavallo et al. (2025) studied this question.

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Observational study evaluates hsCRP and cyclothymic temperament impacting suicidal risk in mood disorders, indicating potential biomarkers.