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This is a Cross-Sectional Study study.

September 16, 2025European PsychiatryOpen Access

The possible role of seasonality and hs-CRP in the evaluation of suicidality risk

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Observational study reveals links between hsCRP and suicidality risk among patients with mood disorders, highlighting seasonality effects.

There is a significant association between seasonality and suicidality risk in mood disorders.
Patients hospitalized in autumn had a lower log-hsCRP, suggesting seasonal effects on inflammation.
Multivariate regression indicated hsCRP levels and seasonal variations significantly correlate with suicidality risk.
Further research is needed to explore the interplay of biological and environmental factors in mental health.

Longo et al. (2025) studied this question.

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Observational study reveals links between hsCRP and suicidality risk among patients with mood disorders, highlighting seasonality effects.