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September 16, 2025NutrientsOpen Access

Targeting the Gut Microbiota in Pediatric Obesity: A Paradigm Shift in Prevention and Treatment? A Comprehensive Review

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Authors

GFGabriele ForcinaUniversity of Campania "Luigi Vanvitelli"PFPierluigi Di FilippoUniversity of Campania "Luigi Vanvitelli"DBDelia De Biasio

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Overview

Comprehensive review reveals gut microbiota interventions can influence pediatric obesity, suggesting new treatment pathways.

Key Points

  • Targeting the gut microbiota may improve metabolic profiles in children with obesity, offering new prevention strategies.
  • Evidence shows that interventions like probiotics and dietary modulation can address gut dysbiosis linked to obesity.
  • Research indicates that gut microbiota impacts metabolism and inflammation, highlighting its role in pediatric obesity.
  • Current findings are promising but limited, necessitating more robust clinical data on microbiota-targeted therapies.

Cite This Study

Forcina et al. (2025) studied this question.

synapsesocial.com/papers/68d4508231b076d99fa5830dhttps://doi.org/10.3390/nu17182942
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Gut Microbiota: An Essential Component in Understanding Pediatric Obesity: A Narrative Review2026 · 2 citations
  2. 2Gut Microbiota: An Important Participant in Childhood Obesity2024 · 42 citations
  3. 3Gut Microbiota Dynamics in Obesity and Metabolic Regulation2025 · 1 citations
  4. 4Gut Microbiota and Short-Chain Fatty Acids: Key Factors in Pediatric Obesity and Therapeutic Targets2025
  5. 5Gut Microbiome Responses to Nutritional and Lifestyle Interventions in Pediatric Obesity: A Systematic Review Toward Precision Nutrition2026