What type of study is this?

This is a Quantitative Study study (also classified as: Experimental Study).

September 16, 2025Scientific ReportsOpen Access

Comprehensive analysis of the tumor immune microenvironment in gastric cancer and peritoneal metastasis based on single-cell RNA sequencing analysis

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Robust cell communication in gastric cancer was observed, highlighting the role of tumor-associated macrophages.
Gene enrichment analyses revealed high expression in pathways like P53 and JAK-STAT3 associated with cancer progression.
Single-cell RNA sequencing identified 13 distinct cell clusters in peritoneal metastasis and gastric cancer samples.
High expression levels of selected genes correlated with poor long-term survival in gastric cancer patients.

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Investigation shows the roles of the tumor microenvironment and CCL5-CCR1 pathway in gastric cancer prognosis.

Sun et al. (2025) studied this question.

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