Cohort analysis examines treatment dynamics with ipilimumab and nivolumab, indicating efficacy in cancer management.
The NABUCCO treatment regimens for cohort 1, 2A and 2B. Cohort 1 was the initial cohort. Later in time, cohort 2 was initiated, in which patients were randomized to cohort 2A (ipilimumab-high) or cohort 2B (ipilimumab-low). Before treatment initiation, tumor tissue was obtained during a transurethral resection of the tumor (lower tract tumors) or via a biopsy (upper tract tumors).
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Stockem et al. (2025) studied this question.
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