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September 16, 2025Open Access

Urine-Based Nematode Chemotaxis Assay (N-NOSE) as a Predictor of Recurrence After Curative Surgery for Resectable Pancreatic Cancer: A Single-Center Prospective Study

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Authors

MFMasahiro FukadaNMNoriki MitsuiTHTakeshi Horaguchi

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Overview

Single-center prospective study identifies N-NOSE and chemotactic behavior as predictors of recurrence in pancreatic cancer patients.

Key Points

  • Pre-treatment N-NOSE positivity is significantly associated with recurrence in resectable pancreatic cancer.
  • During the follow-up, 54.2% of participants experienced cancer recurrence, highlighting the urgency for better monitoring.
  • The study utilized univariate and multivariate analyses to validate predictors of recurrence in patients post-surgery.
  • N-NOSE, a urine-based assay, shows promise as a non-invasive tool for improving postoperative surveillance.

Cite This Study

Fukada et al. (2025) studied this question.

synapsesocial.com/papers/68d4538731b076d99fa58abfhttps://doi.org/10.21203/rs.3.rs-7492933/v1
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  5. 5Predictive factors of actual 5‐y recurrence‐free survival after upfront surgery for resectable pancreatic cancer2024 · 2 citations