What type of study is this?

This is a Quantitative Study study.

September 16, 2025

Altered expression and mutations in cell cycle genes CCND1, CDK4, CDKN2B and TP53 are associated with Pakistani breast cancer patients

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Gene expression analysis highlights associations with breast cancer in Pakistani women, indicating potential biomarkers.

Upregulation of CCND1 and CDK4 occurs in 77.78% and 66.67% of breast cancer samples, respectively.
CDKN2B was found downregulated in 88.89% of cases, showcasing significant gene expression alterations.
Novel mutations in CDK4 were identified, including two missense mutations, indicating genetic diversity in breast cancer.
A nonsense mutation in TP53 potentially disrupts its function, suggesting implications for cancer progression.

Tariq et al. (2025) studied this question.

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