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September 16, 2025PAIN JOINTS SPINEOpen Access

Functional activity of platelets and platelet-leukocyte interaction in rheumatoid arthritis: association with subclinical cardiac involvement

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Authors

KUK. S. UzunBogomolets National Medical University TMTetyana MalchevskaBogomolets National Medical University ITIryna TretyakInstitute of Genetic and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine

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Implication

Observational analysis shows impaired platelet activation correlates with cardiac dysfunction in rheumatoid arthritis, highlighting cardiovascular risk.

Key Points

Impaired platelet activation is evident in rheumatoid arthritis patients, correlating with cardiac dysfunction.
RA patients exhibited significantly lower CD41+/CD62p+ levels compared to those with ischemic heart disease and healthy controls.
Flow cytometry assessed platelet-leukocyte complexes and their relationship with cardiac markers in 124 participants.
These findings suggest that platelet activation may serve as a crucial prognostic marker for cardiovascular risk in rheumatoid arthritis.

Cite This Study

Uzun et al. (2025) studied this question.

synapsesocial.com/papers/68d4538731b076d99fa58b01 https://doi.org/10.22141/pjs.15.3.2025.469

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Implication

Observational analysis shows impaired platelet activation correlates with cardiac dysfunction in rheumatoid arthritis, highlighting cardiovascular risk.

Functional activity of platelets and platelet-leukocyte interaction in rheumatoid arthritis: association with subclinical cardiac involvement

Discussion

Member takes

Implication

Key Points

Cite This Study

Functional activity of platelets and platelet-leukocyte interaction in rheumatoid arthritis: association with subclinical cardiac involvement

Discussion

Member takes

Implication

Key Points

Cite This Study

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