Why the study?
Does active inflammatory arthritis increase platelet reactivity compared to controlled disease in patients without cardiovascular disease?
Population
96 patients with established inflammatory arthritis without a history of cardiovascular disease, diabetes…
Comparison
Active inflammatory disease (n=38) vs Controlled inflammatory disease (n=58)
Design
Cross-sectional
Authors
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Active inflammatory arthritis linked to ADP-specific platelet hyperreactivity; leaves open mechanistic contribution to cardiovascular risk and requires prospective validation.
Does active inflammatory arthritis increase platelet reactivity compared to controlled disease in patients without cardiovascular disease?
Active inflammatory arthritis is associated with enhanced ADP-specific platelet reactivity, which may contribute to the increased cardiovascular risk observed in this population.
Mullan et al. (2009) studied this question.
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