Retrospective analysis revealed no significant difference in magnesium levels between migraine and control groups, suggesting limited role in attack frequency.
The purpose of this study is to compare serum magnesium levels between migraine patients and the control group and to examine the relationship between attack frequency and duration and average serum magnesium level.Patients diagnosed with migraine were included in the study retrospectively. Patients diagnosed with migraine were included as the study group and healthy children presenting to the pediatric neurology clinic in the same period as the control group. The demographic, clinical and laboratory characteristics were recorded.Sixty-one pediatric migraine patients and 50 healthy controls were included in the study. The mean age of the migraine patients was 13.39±3.47 years. Mean magnesium levels were 2.02±0.12 (1.7-2.3) mg/dl in the patient group and 2.05±0.13 (1.8-2.5) mg/dl in the control group, and the difference was not statistically significant (p=0.17). No significant association was determined between attack frequencies and durations and magnesium (p=0.89 and p=0.061, respectively).The role of magnesium among the triggering factors in the etiopathogenesis and in the treatment of migraine is well-established. However, very few previous studies have reported magnesium levels in pediatric migraine patients, and the present research determined no significant difference in serum levels between patients with migraine and a control group.
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Aydın et al. (2025) studied this question.
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