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September 16, 2025European PsychiatryOpen Access

New pharmacological therapies in pure OCD: about a case

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Clinical case shows improvement of obsessive disorder symptoms using off-label pharmacological therapies, suggesting new strategies.

Patient reported significant improvement in obsessive thoughts and functionality with Cariprazine treatment.
Initial treatment with Clomipramine led to side effects, including weight gain and dry mouth.
Switching to Vortioxetine reduced obsessive symptoms but did not resolve cognitive rigidity.
The case highlights the potential of off-label pharmacological therapies in treating obsessive disorder symptoms.

Catherine Bernal (2025) studied this question.

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