Analysis compares intraprostatic lesion visibility using diffusion-weighted imaging in MR-simulator and MR-LINAC, indicating moderate reproducibility.
Motivation: Diffusion-weighted imaging is crucial for identifying ILs in MRgRT. However, DWI quality varies between diagnostic scanners and MR-LINACs, potentially affecting its role in radiotherapy. Goal(s): To investigate IL conspicuity reproducibility using DWI at different b-values and ADC maps on 1.5T MR-simulator and MR-LINAC systems. Approach: Compared DW images from 19 prostate cancer patients on both systems. An expert rated lesion conspicuity on a 3-point scale, with statistical analysis performed to assess reproducibility and differences. Results: Moderate reproducibility between systems, with MR-simulator showing better IL visualization and b1400 images performed best. Findings of this study emphasize the need for improved DWI quality on MR-LINACs. Impact: This study reveals moderate reproducibility of intraprostatic lesion conspicuity between MR-simulator and MR-LINAC systems. Findings underscore the need for improved DWI quality and standardized protocols in MR-guided radiotherapy.
No takes yet. Share an insight, caveat, or question.
Wong et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: