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September 17, 2025Endocrine ConnectionsOpen Access

Trend in Body Mass Index During Childhood in 460 Girls with Idiopathic Central Precocious Puberty

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Authors

AVAlfredo VicinanzaOAO Oli AtomssaANAndrea Nebbioso

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Overview

Retrospective analysis tracked BMI increases during six years prior to puberty onset in girls, suggesting risk factors.

Key Points

  • Significant increase in BMI SDS was observed in girls during the six years preceding pubertal onset.
  • The most rapid BMI rise occurred between six to three years before onset at +0.21 SDS/year.
  • All subgroups—sporadic, familial, and adopted—showed similar BMI trajectory patterns overall.
  • Overrepresentation of girls born small for gestational age and adopted indicates a potential genetic and environmental link.

Cite This Study

Vicinanza et al. (2025) studied this question.

synapsesocial.com/papers/68d45b0b31b076d99fa5cf3dhttps://doi.org/10.1530/ec-25-0215
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Girls with idiopathic central precocious puberty did not display substatial changes in body mass index after treatment with gonadotropin‐releasing hormone analogues2024 · 4 citations
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  3. 3Transitions in stress, depression, and self-esteem across pubertal onset in children with central precocious puberty2026
  4. 4Bone and body composition by DXA in girls with precocious puberty, premature thelarche, and prepubertal controls2026 · 2 citations
  5. 5Breastfeeding, Prepubertal Adiposity, and Development of Precocious Puberty2025 · 5 citations