Pancreatic T1, T2, T2* and PDFF values in healthy pancreas and spectrum of pancreatitis

Motivation: To gain a better understanding of the change in tissue micro-structural properties in healthy and diseased pancreas Goal(s): To study the quantitative MR parameters of pancreas in patients with acute pancreatitis, chronic pancreatitis vs normal group Approach: T1, T2, T2* and PDFF values of the pancreas in patients with Acute Pancreatitis, Chronic Pancreatitis, normal subjects and subjects with normal pancreas who had prior history of pancreatitis were measured prospectively Results: The T1 and T2 values showed significant difference between the groups. No difference was observed between the normal and normal with prior history of pancreatitis groups Impact: Multiparametric MRI of pancreas can reveal tissue properties which are not apparent to the naked eye on conventional MRI sequences, and can help assess pancreatic health, identify subclinical disease, and potentially predict the nature course of illness.