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September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Multi-Modal Imaging Assessment of Neurovascular Uncoupling in Alzheimer's Disease and Related Dementia

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Regional neurovascular and metabolic dysregulation was identified across Alzheimer's disease stages, leading to better diagnostic criteria.
Clinical assessments using ASL-MRI and 18F-FDG PET revealed Type 1 and Type 2 uncoupling in MCI regions.
The study established an analytical method for early, non-invasive detection of dysregulation in Alzheimer's disease.
This approach supports improved early diagnosis, potentially enhancing treatment strategies and reducing healthcare burdens.

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Implication

Retrospective analysis reveals regional dysregulation in neurovascular and metabolic systems in Alzheimer's disease, suggesting new diagnostic approaches.

Cite This Study

Persohn et al. (2025) studied this question.

synapsesocial.com/papers/68d45b1b31b076d99fa5d439 https://doi.org/10.58530/2025/5410

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Implication

Retrospective analysis reveals regional dysregulation in neurovascular and metabolic systems in Alzheimer's disease, suggesting new diagnostic approaches.

Multi-Modal Imaging Assessment of Neurovascular Uncoupling in Alzheimer's Disease and Related Dementia

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Discussion

Implication

Cite This Study

Multi-Modal Imaging Assessment of Neurovascular Uncoupling in Alzheimer's Disease and Related Dementia

Key Points

Discussion

Implication

Cite This Study

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