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September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Changes in Cerebral Small Vessel Density and Hemodynamics in CADASIL Patients Revealed by high-resolution Black-Blood MRI and Multi-Delay pCASL

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Authors

ZYZidong YangZLZi-Xuan LiuFGFanhua Guo

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Overview

Observational analysis reveals changes in cerebral hemodynamics and small vessel density in CADASIL, suggesting links to cognitive impairments.

Key Points

  • CADASIL patients show significant reductions in cerebral small vessel density and CBF.
  • Alterations in ATT were observed across multiple brain regions in CADASIL patients.
  • Associations exist between changes in cerebral hemodynamics and cognitive ability.
  • High-resolution black blood MRI and pCASL were utilized for comprehensive assessments.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68d45b1b31b076d99fa5d4dchttps://doi.org/10.58530/2025/4356
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of Small Vessel Density Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalophy (<scp>CADASIL</scp>) by High‐Resolution Black‐Blood <scp>MRI</scp>2025 · 3 citations
  2. 2Varying Impacts of MRI-Detected Lesions on Cognitive Function in CADASIL Patients2025
  3. 3Small vessel dysfunction at 7T MRI locally predicts white matter damage progression in CADASIL2025
  4. 4Abstract DP245: Retinal Vessel Dysfunction in CADASIL: an Ultra-Widefield Fluorescein Angiography Study2026
  5. 5Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease2021 · 39 citations