What type of study is this?

September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Genetic Influences on Brain Aging: Analyzing Sex Differences in the UK Biobank using Structural MRI

View Full Paper

Ask AI

Bookmark

Authors

KAKaren ArdilaUniversity of Calgary AMAashka Mohite AAAbdoljalil AddehMount Royal University

Discussion

Member takes

Implication

Observational analysis reveals sex-specific genetic variants linked to brain aging in the UK Biobank, suggesting tailored approaches for neurodegeneration.

Key Points

Sex-stratified analyses uncovered distinct genetic variants related to brain aging, indicating crucial differences in neurobiology.
Key findings include neurotransmitter-related genes in females and immune response genes in males, highlighting sex differences.
Implementation of Brain Age Gap Estimates complemented by post-GWAS analyses provided insights into genetic pathways affecting brain aging.
Understanding genetic contributions to brain aging may enable personalized treatment strategies for neurodegeneration tailored by sex.

Cite This Study

Ardila et al. (2025) studied this question.

synapsesocial.com/papers/68d45b1b31b076d99fa5d4f6 https://doi.org/10.58530/2025/1500

View Full Paper

Ask AI

Bookmark

Implication

Observational analysis reveals sex-specific genetic variants linked to brain aging in the UK Biobank, suggesting tailored approaches for neurodegeneration.

Genetic Influences on Brain Aging: Analyzing Sex Differences in the UK Biobank using Structural MRI

Discussion

Member takes

Implication

Key Points

Cite This Study

Genetic Influences on Brain Aging: Analyzing Sex Differences in the UK Biobank using Structural MRI

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider