Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 17, 2025Iranian Journal of Public HealthOpen Access

The Correlation of Blood Immune Cells with the Pathogenesis of Schizophrenia: A Meta-Analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

FXFengyu XueZLZhijun LiLYLijuan Yan

Discussion

Loading...

Member takes

Overview

Meta-analysis reveals increased immune cell counts in schizophrenia patients, suggesting immune dysfunction might play a role.

Key Points

  • Schizophrenia patients show significantly higher white blood cell counts compared to controls, indicating immune involvement.
  • Meta-analysis included 42 studies, highlighting a strong association between high CD4 counts and schizophrenia symptoms.
  • The systematic review followed PRISMA guidelines, ensuring comprehensive assessment and reporting of findings.
  • Findings highlight the potential for immune dysfunction to contribute to the pathogenesis of schizophrenia, warranting further research.

Cite This Study

Xue et al. (2025) studied this question.

synapsesocial.com/papers/68d4604031b076d99fa5f2cahttps://doi.org/10.18502/ijph.v54i8.19566
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The causal relationship between immune cell traits and schizophrenia: a Mendelian randomization analysis2024 · 10 citations
  2. 2Immune factors associated with prominent negative symptoms and disease severity in schizophrenia2024
  3. 3The relationship between peripheral immune cell markers and cognitive functions in patients with schizophrenia2024 · 2 citations
  4. 4Evaluation of haematological parameters in patients with first-episode psychosis: distinctions between bipolar disorder and schizophrenia spectrum disorders2026
  5. 5Research Hotspots and Emerging Trends of Schizophrenia and Immune Response: A Bibliometric Analysis2025