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September 17, 2025Advanced medical journalOpen Access

Corticosteroids vs. Combined Corticosteroid/Antiviral Therapy in Bell's Palsy Treatment: A Randomized Controlled Trial

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Authors

RSRanj SalaeiSHShehab Ahmed HamadAAAhmed Alraad

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Overview

Randomized trial shows combination therapy improves recovery in Bell's palsy, suggesting better outcomes.

Key Points

  • Combination therapy with corticosteroids and antivirals led to a recovery rate of 89% in Bell's palsy patients, surpassing the 78% recovery of corticosteroids alone.
  • At 12 weeks, the complete recovery rate was 72% for combination therapy compared to 61% for monotherapy, indicating a significant difference.
  • This randomized, double-blind, placebo-controlled trial involved 36 patients presenting within 72 hours of symptom onset.
  • Combination therapy shows promising benefits in Bell's palsy treatment, with faster recovery times and higher effectiveness.

Cite This Study

Salaei et al. (2025) studied this question.

synapsesocial.com/papers/68d4604031b076d99fa5f4fahttps://doi.org/10.56056/amj.2025.388
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of Combination and Single Therapy in Bell's Palsy: A Systematic Review and Meta-Analysis.2025
  2. 2Comparative Analysis of Treatment Modalities for Bell's Palsy and Their Effectiveness2025
  3. 3Corticosteroids and antiviral treatment for Bell's palsy (idiopathic facial paralysis)2026
  4. 4A meta-analysis and modelling of the duration of symptoms in Bell’s palsy in the Scottish and Scandinavian trials2025
  5. 5Steroid administration facilitates recovery in severe refractory Bell’s palsy patients who did not receive steroids in the acute stage: a retrospective study2026