Lamin-related dilated cardiomyopathy

Lamin-related dilated cardiomyopathy is a genetic disease that causes rapidly progressive heart failure (HF), various arrhythmias and conduction disorders, and it is associated with a high risk of sudden cardiac death (SCD). The article presents a clinical case of a patient with cardiomyo- pathy caused by mutations in the LMNA gene, its early manifestations being rapidly progressive HF, ventricular systolic dysfunction, valvular abnormalities, supraventricular and ventricular rhythm and conduction disorders. The case study shows the evolution of clinical manifestations during the follow-up period, as well as discusses the risk stratification of sudden cardiac death and the strategy of its prevention.