Population
Patients with lamin A/C heart disease (LMNA mutations) and dilated cardiomyopathy
Design
Review
Authors
Discussion
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Member takes
Implication
May prompt earlier genetic testing and ICD evaluation in DCM; leaves open prospective validation of risk stratification algorithms.
Structured PICO
P
Population
Patients with lamin A/C heart disease (LMNA mutations) and dilated cardiomyopathy
Lamin A/C heart disease is a highly malignant form of dilated cardiomyopathy requiring early ICD implantation and personalized risk stratification.
Cite This Study
Captur et al. (2017) studied this question.