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September 18, 2025Physics in Medicine and Biology

Optimizing the Ferumoxytol dose for vascular suppression in brachial plexus magnetic resonance neurography

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Authors

ALA.M. LoweCurtin UniversityDSDarryl B. SneagHospital for Special SurgerySTShayna TurbinHospital for Special Surgery

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Overview

Evaluation of subject-specific ferumoxytol dosing for improved vascular suppression during magnetic resonance neurography, indicating better nerve visualization.

Key Points

  • Improved vascular suppression achieved with subject-specific ferumoxytol dosing in brachial plexus MRN.
  • Cohort 3 exhibited better results with lower vessel-muscle contrast ratios compared to variable dosing.
  • Higher correlations were found between vein-muscle contrast ratios and subject-specific dosing than absolute dosing.
  • Doses of ferumoxytol were estimated at 101.49 mg to achieve a target contrast ratio for effective vascular suppression.

Cite This Study

Lowe et al. (2025) studied this question.

synapsesocial.com/papers/68d461b631b076d99fa60825https://doi.org/10.1088/1361-6560/ae0864
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Subject-specific Dose of Ferumoxytol for Vascular Suppression in Brachial Plexus Magnetic Resonance Neurography2025
  2. 2Lymph Node Suppression with Simultaneous Vascular Suppression on Ferumoxytol-Enhanced Magnetic Resonance Neurography2025
  3. 3Ferumoxytol dose optimization for three-dimensional whole-heart magnetic resonance imaging in patients with congenital heart disease2026 · 1 citations
  4. 4Delayed Ferumoxtran‐10‐Enhanced Magnetic Resonance Neurography of the Lumbosacral Plexus: Impact on Vascular Suppression and Image Quality2024 · 1 citations
  5. 5Exploring the Diagnostic Utility of Ferumoxytol for Brachial Plexus MR Neurography2026