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September 18, 2025Delta Journal of OphthalmologyOpen Access

Assessment of early macular and peripapillary diabetic vascular changes using optical coherence tomography angiography

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Authors

RHRagai Magdy HatataSAShehab M. AbdelFadeelAAAsser A.E. Abdel-Meguid

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Overview

Prospective case-control study shows lower macular vascular density in diabetic patients, indicating potential early signs of diabetic retinopathy.

Key Points

  • Significant reductions in macular perfusion density were observed in diabetic patients without retinopathy compared to healthy controls.
  • The number of branches in the macular vascular structure significantly decreased in diabetic patients compared to healthy participants.
  • Peripapillary vascular parameters also showed significant reductions in patients with diabetes, indicating early vascular changes.
  • Analysis utilized optical coherence tomography to evaluate vascular characteristics in diabetic patients against healthy controls.

Cite This Study

Hatata et al. (2025) studied this question.

synapsesocial.com/papers/68d461bc31b076d99fa60c84https://doi.org/10.4103/djo.djo_12_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography-Angiography in Diabetic Patients2024 · 1 citations
  2. 2Changes in peripapillary microvasculature and retinal nerve fibre layer in diabetes and diabetic retinopathy using optical coherence tomographic angiography: a community-based, cross-sectional study2025
  3. 3Peripapillary Retinal and Choroidal Vasculature in Patients with Diabetes of Different Durations without Clinical Diabetic Retinopathy2026 · 1 citations
  4. 4Evaluation of glaucomatous macular and optic nerve vascular damage by optical coherence tomography angiography2024
  5. 5Early retinal, optic disc and choriocapillaris microvascular alterations in children with type 1 diabetes without clinical retinopathy: an OCTA-based case–control study2026