This research demonstrates the synthesis of polypeptides using N-carboxyanhydride, highlighting the potential for functionalization with reducing oligosaccharides.
N-carboxyanhydride (NCA) ring-opening polymerization offers an attractive approach for the construction of polypeptides. Here, we report the synthesis of a serine NCA-functionalized monomer bearing a methylaminooxy group, enabling post-polymerization attachment...
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Palmieri et al. (2025) studied this question.
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