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September 18, 2025Frontiers in NeurologyOpen Access

Size of affected vessels in primary angiitis of the CNS: associations with clinical features, medical management and functional outcomes

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Patients with exclusive small vessel involvement showed greater functional decline and more severe imaging progression.
Biopsies were positive exclusively in cases with small vessel involvement, highlighting a critical association.
Cyclophosphamide usage was significantly higher in patients with small vessel involvement compared to others.
This study emphasizes the importance of vessel size in determining PACNS clinical features and management.

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Retrospective study identifies vessel size involvement in PACNS, suggesting connections with functional outcomes and management strategies.

Frank et al. (2025) studied this question.

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Retrospective study identifies vessel size involvement in PACNS, suggesting connections with functional outcomes and management strategies.