In this paper, we develop a concise differential–potential framework for the functions of a generalized quaternionic variable in the two-parameter algebra Hα, β, with α, β∈R∖0. Starting from left/right difference quotients, we derive complete Cauchy–Riemann (CR) systems and prove that, away from the null cone where the reduced norm N vanishes, these first-order systems are necessary and, under C1 regularity, sufficient for left/right differentiability, thereby linking classical one-dimensional calculus to a genuinely four-dimensional setting. On the potential theoretic side, the Dirac factorization Δα, β=D¯D=DD¯ shows that each real component of a differentiable mapping is Δα, β-harmonic, yielding a clean second-order theory that separates the elliptic (Hamiltonian) and split (coquaternionic) regimes via the principal symbol. In the classical case (α, β) = (−1, −1), we present a Poisson-type representation solving a model Dirichlet problem on the unit ball B⊂R4, recovering mean-value and maximum principles. For computation and symbolic verification, real 4×4 matrix models for left/right multiplication linearize the CR systems. Examples (polynomials, affine CR families, and split-signature contrasts) illustrate the theory, and the outlook highlights boundary integral formulations, Green kernel constructions, and discretization strategies for quaternionic PDEs.
Ji Eun Kim (Tue,) studied this question.