This method demonstrates efficient bond construction in 2-oxazolidinones from propargylamines and CO2, indicating sustainable chemical synthesis benefits.
The electrochemical conversion of CO2 into value-added chemicals represents a promising strategy for sustainable synthesis. Herein, we report a novel electrochemical carboxylative cyclization of propargylamines with CO2 to access exocyclic iodo-carboxyl-vinylene 2-oxazolidinones bearing two CO2 moieties by using tetraethylammonium iodide (Et4NI) as both the electrolyte and the "iodine source", which enables the one-pot construction of C–O, C–C, C–N, and C–I bonds. The protocol proceeds under mild conditions and accommodates a broad range of substrates, providing access to functionalized 2-oxazolidinones with high structural complexity.
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Meng et al. (2025) studied this question.
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