This method demonstrates efficient selective reduction of quinolines with copper salt, indicating broader synthetic applications.
A highly efficient selective reduction of quinolines with silanes was achieved under the catalysis of a copper salt. This protocol provides access to a wide range of synthetically useful 1,2,3,4-tetrahydroquinolines under mild reaction conditions. Furthermore, the synthetic potential is further demonstrated through facile transformations to obtain valuable bioactive molecules.
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Zhang et al. (2025) studied this question.
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