What type of study is this?

This is a Quantitative Study study (also classified as: Cohort Study).

September 18, 2025Acta NeuropathologicaOpen Access

Limbic Alzheimer’s co-pathology in multiple system atrophy is associated with cognitive impairment and diagnostic inaccuracy

View Full Paper

Ask AI

Bookmark

Authors

Analysis reveals that amyloid-beta and tau pathologies in MSA correlate with cognitive decline, indicating diagnostic challenges.

Cognitive impairment significantly associates with limbic Aβ and p-tau pathologies in MSA cases.
High percentages of amyloid-beta (31%) and phosphorylated-tau (91%) pathology were identified among MSA donors.
Analysis utilized a well-characterized autopsy cohort, assessing co-pathologies in limbic brain regions.
Results emphasize the need for improved diagnostic criteria and better biomarker strategies in MSA.

Wetering et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark