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September 19, 2025Open Access

Human Papillomavirus: An Old New History

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This review highlights HPV epidemiology and prevention strategies in adolescents, indicating cultural barriers affect vaccination rates.

Human papillomavirus (HPV) is the most common sexually transmitted infection, affecting nearly all sexually active individuals.
Over 200 genotypes of HPV exist, with high-risk types linked to various cancers, notably cervical and anogenital cancers.
Many HPV infections resolve spontaneously, but persistent high-risk types can lead to severe health issues, necessitating effective screening.
Innovative strategies like vaccination and microbiome modulation are crucial to improving HPV prevention, especially in adolescents.

West et al. (2025) studied this question.

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