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This is a Literature Review study.

October 15, 2025JURNAL BIOLOGI TROPISOpen Access

Human Papillomavirus (HPV) Infection and The Spectrum of Diseases It Causes: A Literature Review

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Literature review highlights major health risks of HPV infection in populations, suggesting improved vaccination efforts.

HPV infection is a major cause of both benign and malignant diseases due to persistent cell transformation.
High-risk HPV types, mainly HPV 16 and 18, are strongly linked to cancer, while low-risk types typically cause genital warts.
Primary vaccination against HPV is critical in reducing disease burden, especially with the expansion to school-aged girls.
New-generation therapeutic vaccines suggest promising advancements in HPV management, addressing existing treatment gaps.

Hanifah et al. (2025) studied this question.

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