September 19, 2025Open Access

The Role and Safety of Plant Derived Nutraceuticals as Adjuvant Treatment for Pain Management: A Narrative Review

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Nutraceuticals may reduce the negative impact of prescription drugs on patient health, enhancing pain management.
Evidence indicates strong anti-nociceptive effects of escin and green tea, supporting their role in pain relief.
A fixed nutraceutical formulation including glutathione and silymarin can help manage pain effectively, especially in elderly patients.
The review highlights the potential of nutraceuticals in polytherapy, reducing the need for higher drug dosages.

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Narrative review assesses efficacy and safety of plant derived nutraceuticals for pain management, suggesting potential as adjuvant treatment.

Marcianò et al. (2025) studied this question.

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Narrative review assesses efficacy and safety of plant derived nutraceuticals for pain management, suggesting potential as adjuvant treatment.