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This is a Quantitative Study study.

September 19, 2025Open Access

Aging diminishes interlaminar functional connectivity in the mouse cortical V1 and CA1 hippocampal regions

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Aging significantly impairs functional connectivity in cortical and hippocampal networks.
Aged mice exhibited reduced local field potential power and coherence across frequency bands.
Chronic electrophysiological recordings were conducted in the mouse primary visual cortex and CA1 region.
Study results highlight the need for multi-region assessments to understand aging brain vulnerabilities.

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Implication

Chronic recordings reveal aging impairs functional connectivity in cortical and hippocampal regions, suggesting potential targets for preserving cognitive health.

Cite This Study

Thai et al. (2025) studied this question.

synapsesocial.com/papers/68d464e031b076d99fa63bc0 https://doi.org/10.1101/2025.09.17.676336

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Implication

Chronic recordings reveal aging impairs functional connectivity in cortical and hippocampal regions, suggesting potential targets for preserving cognitive health.

Aging diminishes interlaminar functional connectivity in the mouse cortical V1 and CA1 hippocampal regions

Key Points

Discussion

Implication

Cite This Study

Aging diminishes interlaminar functional connectivity in the mouse cortical V1 and CA1 hippocampal regions

Key Points

Discussion

Implication

Cite This Study

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