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Abstract B131: Association between type 2 diabetes and prevalence of monoclonal gammopathy of undetermined significance in a large screened U.S. population

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No significant association found between type 2 diabetes and MGUS prevalence, challenging previous assumptions.
Age- and sex-adjusted odds ratios indicated a lower prevalence of MGUS in those with a history of type 2 diabetes.
Logistic regression analysis across diverse cohorts highlighted complexity in the relationship between diabetes and MGUS.
Racial disparities in health outcomes may complicate understanding of both MGUS and diabetes associations.

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Analysis reveals no strong link between type 2 diabetes and MGUS prevalence in diverse cohorts, suggesting racial disparities may influence findings.

Holder et al. (2025) studied this question.

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Analysis reveals no strong link between type 2 diabetes and MGUS prevalence in diverse cohorts, suggesting racial disparities may influence findings.