This literature review evaluates clinicopathological features and treatments for tubulointerstitial lupus nephritis, suggesting improved diagnosis.
Background Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that affects multiple organ systems, and lupus nephritis (LN) primarily involves glomerular, vascular and tubulointerstitial lesions. Renal tubulointerstitial lesions are almost always present alongside glomerular lesions, with isolated renal tubulointerstitial LN being very rare. The aim of this study was to evaluate the clinicopathological features, differential diagnosis, treatment and prognosis of predominant tubulointerstitial lupus nephritis (PTILN).
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Wang et al. (2025) studied this question.
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