September 19, 2025Frontiers in MedicineOpen Access

Management of severe pneumonia in respiratory non-intensive care unit: a retrospective study from a single center experience

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Discussion

Retrospective study identifies risk factors and treatment strategies for severe pneumonia, highlighting key differences in severity outcomes.

Severe pneumonia cases had a Pneumonia Severity Index greater than 90 in 61.53% of cases compared to 41.31% in non-severe pneumonia.
The Charlson Comorbidity Index was higher in severe pneumonia patients, indicating lower survival rates due to comorbidities at 84.61% versus 61.23%.
The use of high-flow nasal cannula was significantly higher in severe cases at 69.23%, with a notable difference in CPAP usage as well.
Antibiotic therapy duration was longer in severe pneumonia cases, averaging 14.69 days versus 11.77 days in non-severe patients.

Pisanu et al. (2025) studied this question.

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Retrospective study identifies risk factors and treatment strategies for severe pneumonia, highlighting key differences in severity outcomes.