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January 1, 1985Archives of Physiology and Biochemistry

Severe Community-acquired Pneumonia: Factors Influencing Need of Intensive Care Treatment and Prognosis

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Authors

ÅÖÅke ÖrtqvistKarolinska InstitutetGSG SternerBoston Children's HospitalJNJ. Axel NilssonLund University

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Implication

Retrospective study reveals a 25% acute mortality rate in severe community-acquired pneumonia requiring intensive care, highlighting advanced age and low leukocyte count as key risk factors.

Key Points

  • To examine the predisposing factors, microbiological causes, treatment requirements, and prognostic determinants of mortality in patients admitted to an intensive care unit with severe community-acquired pneumonia.
  • Retrospective review of 53 patients with severe community-acquired pneumonia admitted to an intensive care unit.
  • Evaluation of underlying conditions, identified pathogens, necessity for mechanical ventilation, and mortality across hospital admission and an average follow-up of 3.25 years.
  • Predisposing factors were documented in 77% of patients, and an etiology was confirmed in 53%, primarily Streptococcus pneumoniae.
  • Immediate active intervention was required in 70% of patients and mechanical ventilation in 58%, yielding an acute mortality of 25% (32% among mechanically ventilated patients) and a long-term mortality of 39%.
  • Significantly elevated mortality was linked to older age, prior immunocompromised status, and admission leukocyte counts ≤ 9 × 10⁹/L.

Cite This Study

Örtqvist et al. (1985) studied this question.

synapsesocial.com/papers/6a772dfade5e3adfbdf6f93ahttps://doi.org/10.3109/13813458509058778
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