September 19, 2025

[Clinical analysis of anti-GT1a antibody-positive Guillain-Barré syndrome in 25 children].

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Limb weakness and bulbar palsy were the main neurological manifestations in children with anti-GT1a antibody-positive GBS.
84% of the children received intravenous immunoglobulin (IVIG), leading to favorable outcomes and low residual disability.
Cerebrospinal fluid analysis showed albuminocytological dissociation in 18 out of 23 children, indicating demyelinating changes.
Outcomes suggested that relapses are rare but manageable with re-treatment, highlighting the importance of follow-up care.

Authors

DCD ChenGuangzhou Women and Children Medical Center CHChi HouGuangzhou Women and Children Medical Center HZHaifeng ZhuBoeing (Australia)

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Implication

Case series highlights limb weakness and bulbar palsy in children with anti-GT1a antibody-positive Guillain-Barré syndrome, suggesting effective IVIG treatment.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68d466b531b076d99fa65860 https://doi.org/10.3760/cma.j.cn112140-20250716-00640

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Implication

Case series highlights limb weakness and bulbar palsy in children with anti-GT1a antibody-positive Guillain-Barré syndrome, suggesting effective IVIG treatment.

[Clinical analysis of anti-GT1a antibody-positive Guillain-Barré syndrome in 25 children].

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Implication

Cite This Study

[Clinical analysis of anti-GT1a antibody-positive Guillain-Barré syndrome in 25 children].

Key Points

Discussion

Implication

Cite This Study

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