An [3 + 3] annulation generates chromeno[2,3-b]pyridinones in a single operation, highlighting efficient chemistry.
An [3 + 3] annulation of 2‐aminochromen‐4‐ones with substituted benzylidene Meldrum's acids has been developed. This reaction included a sequential intermolecular Michael addition/intramolecular nucleophilic addition/ring opening of Meldrum's acid/ removal of acetone/decarboxylation sequence, which possessed excellent step in a single operation for direct generating to substituted chromeno[2,3‐ b ]pyridinones from readily available substrates.
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Lv et al. (2025) studied this question.
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