Diversity‐Oriented Synthesis of 2‐Aryl‐ 5 H ‐Chromeno[4,3‐ b ]Pyridines via a One‐Pot Sequential Michael/Cyclization Process

The synthesis of 2‐aryl‐5 H ‐chromeno[4,3‐ b ]pyridine derivatives has drawn considerable interest owing to their pharmaceutical relevance. A concise protocol was presented for the construction of these frameworks through an NH 4 OAc‐promoted cascade Michael/cyclization process involving aromatic aldehydes, β‐ketonitriles, and chroman‐4‐ones. Using the optimal conditions, the target products were isolated in moderate to excellent yields. This approach offers wide substrate scope, simple workup, and proceeds without an inert atmosphere.