Synthesis of 2H-Chromeno[2,3-b]tetrahydropyridine Frameworks through Cs₂CO₃-Promoted Annulation of 2-Amino-4H-chromen-4-ones and 4-Benzylideneoxazol-5(4H)-ones

This innovative reaction involved the [3+3] annulation of 2-amino-4H-chromen-4-ones and 4-benzylideneoxazol-5(4H)-ones. The process provided quick and easy access to a broad range of structurally diverse and highly functionalized 1,3,4,5-tetrahydro-2H-chromeno[2,3-b]pyridines in moderate to good yields, which possess trans-form C3 and C4 substituents.